Analytical Chemistry

Analytical chemistry began in the late eighteenth century with the work of French chemist Antoine-Laurent Lavoisier and others; the discipline was further developed in the nineteenth century by Carl Fresenius and Karl Friedrich Mohr. As a pharmacist's apprentice in Frankfurt, Germany, Fresenius developed an extensive qualitative analysis scheme that, when it was later published, served as the first textbook of analytical chemistry. He built a laboratory at his house that opened in 1848. Here he trained students in gravimetric techniques that he had developed. Mohr developed laboratory devices such as the pinch clamp burette and the volumetric pipette. He also devised a colorimetric endpoint for silver titrations. It was his 1855 book on titrimetry, Lehrbuch der Chemisch-Analytischen Titromethode , that generated widespread interest in the technique.

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