Enantioselective organocatalysis has become a field of central importance for the asymmetric synthesis of chiral molecules. In the last ten years alone, this field has grown at an extraordinary pace from a small collection of chemically unique reactions to a thriving area of general concepts, atypical reactivities, and widely applicable reactions. Moreover, novel modes of substrate activation have been achieved using organic catalysts that can now deliver unique, orthogonal, or complementary selectivities in comparison to many established metal-catalyzed transformations. For more details click here.
Image courtesy of Prof. D. Savoia |
Courtesy: Dr. Gérald Lelais, Professor D. W. C. MacMillan, http://www.princeton.edu
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