An interdisciplinary study led by Dr Ali Tavassoli, a Reader in chemical
biology at the University of Southampton, has shown for the first time
that 'click chemistry' can be used to assemble DNA that is functional in
human cells, which paves the way for a purely chemical method for gene
synthesis.
Writing in Angewandte Chemie International Edition Dr Tavassoli's team and his collaborators, Dr Jeremy Blaydes and Professor Tom Brown, show that human cells can still read through strands of DNA correctly despite being stitched together using a linker not found in nature.
Writing in Angewandte Chemie International Edition Dr Tavassoli's team and his collaborators, Dr Jeremy Blaydes and Professor Tom Brown, show that human cells can still read through strands of DNA correctly despite being stitched together using a linker not found in nature.
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| Credit: University of Southampton |
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