The Reimer-Tiemann reaction is an organic reaction used to convert a
phenol to an o-hydroxy benzalde-hyde using chloroform, a base, and acid
work-up.
The mechanism begins with abstraction of the proton from
chloroform with the base to form a trichlorocarbanion which
spontaneously loses a chloride ion to form a neutral dichlorocarbene.
The base also deprotonates the phenol reagent which then attacks the
carbene.
A series of steps and a final acid work-up result in the
o-hydroxy benzaldehyde product. For more click here.
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| Image Credit: chemistry.tutorvista.com |
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